Ipomoea carnea Jacq. ameliorates formalin-induced paw inflammation in rats through modulation of oxidative and inflammatory pathways.

Inflammopharmacology · 2025

Formaldehyde.

Dermatitis : contact, atopic, occupational, drug · 2015

Formaldehyde is a potent contact allergen, and updated patch test protocols are required to accurately diagnose formaldehyde-allergic patients.

Formaldehyde Promoted Tumor Cell Growth Through Reinforced Lactylation of Poly (ADP-Ribose) Polymerase 1.

Journal of applied toxicology : JAT · 2025

Formaldehyde toxicity.

Archives of pathology & laboratory medicine · 1979

Formaldehyde acts as both a primary irritant and a sensitizing agent, with some individuals exhibiting allergic responses at concentrations below the odor threshold.

Transgenerational Reproductive and Developmental Toxicity Induced by N-Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster.

Journal of applied toxicology : JAT · 2025

Formaldehyde stress.

Science China. Life sciences · 2010

Elevated formaldehyde levels contribute to 'formaldehyde stress,' inducing protein misfolding and potential cellular dysfunction linked to cognitive decline.

Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute Cohort.

Journal of the National Cancer Institute · 2009

In the NCI cohort of 25,619 formaldehyde-exposed workers followed for a median of 42 years, the highest peak exposure category, 4 ppm or greater, was associated with significantly increased mortality from all lymphohematopoietic malignancies and Hodgkin lymphoma, with elevated risks also seen for leukemia and myeloid leukemia. This supports formaldehyde as a serious occupational carcinogen.

Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.

Journal of the National Cancer Institute · 2009

Among funeral industry workers, mortality from myeloid leukemia rose significantly with increasing years of embalming and with increasing peak formaldehyde exposure. Workers with more than 34 years of embalming had markedly elevated myeloid leukemia mortality, reinforcing a dose-related cancer risk from formaldehyde exposure.

Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2010

In 94 Chinese workers, including 43 exposed to formaldehyde, exposed workers had significantly reduced peripheral blood cell counts and significantly increased leukemia-specific chromosome changes, including monosomy 7 and trisomy 8, in cultured myeloid progenitor cells. The study provides direct human mechanistic evidence that formaldehyde damages the hematopoietic system in ways relevant to leukemia.