No ads. No brand influence.Powered by members like you.
other
Grade reflects published research findings and regulatory status. Not a safety certification.
Ingredient evidence is still under review.
Presence ≠ Risk. Educational summary only. Not medical advice.
Per- and polyfluoroalkyl substances (PFAS) and human health: A review of the literature
Science of the Total Environment · 2020
The study summarizes evidence that PFAS exposure is associated with adverse health effects including immunotoxicity, endocrine disruption, and increased risk of certain cancers.
View on PubMed
Per- and polyfluoroalkyl substances (PFAS) and their associations with obesity, cardiovascular disease, and hypertension in the US population
Environmental Research · 2020
This study identified significant positive associations between serum PFAS concentrations and markers of cardiovascular disease, hypertension, and obesity in the US adult population.
View on PubMed
Per- and polyfluoroalkyl substances (PFAS) and their association with metabolic health: A systematic review and meta-analysis
Environmental Research · 2021
Evidence suggests a positive association between exposure to specific PFAS compounds and increased serum cholesterol and insulin resistance in human populations.
View on PubMed
PFAS exposure and thyroid disease: A systematic review and meta-analysis
Environmental Research · 2021
Meta-analysis indicates that elevated serum PFAS levels are significantly associated with thyroid hormone dysregulation and increased prevalence of thyroid disease in humans.
View on PubMed
PFAS exposure and immune response to vaccines: A systematic review and meta-analysis
Environmental Research · 2021
The analysis demonstrates a significant inverse relationship between PFAS exposure levels and antibody response to various vaccines, indicating potential immunotoxicity.
View on PubMed
Immunotoxicity of per- and polyfluoroalkyl substances (PFAS) in humans: A systematic review
Environmental Health Perspectives · 2021
Analysis indicates that PFAS exposure is significantly associated with suppressed vaccine response and increased risk of infectious diseases in both children and adults.
View on PubMed
Exposure to perfluoroalkyl substances and cancer risk in a population-based cohort
International Journal of Cancer · 2022
The study suggests positive associations between specific PFAS exposures and the incidence of certain hormone-related cancers, supporting potential carcinogenic pathways.
View on PubMed
Endocrine-disrupting effects of per- and polyfluoroalkyl substances: A systematic review and meta-analysis
Reviews on Environmental Health · 2020
The review highlights consistent evidence of thyroid hormone disruption and adverse reproductive health effects resulting from PFAS exposure.
View on PubMed
Per- and polyfluoroalkyl substances (PFAS) in blood and the risk of thyroid cancer
Environmental Research · 2021
Epidemiological findings suggest a positive association between serum concentrations of long-chain PFAS and the incidence of thyroid cancer.
View on PubMed
FDA: no ruling
IARC: not evaluated
Grades are based on published peer-reviewed research, regulatory agency data (FDA, EU, IARC, WHO, EPA), and independent analysis. We update entries when new findings emerge.
other
High concern
Ingredient evidence is still under review.
EU: restricted with limits
varies by specific PFAS; multiple PFAS are banned or restricted under EU REACH/POPs measures
View sourceEPA: no reference dose found
California Prop 65: not listed
Per- and polyfluoroalkyl substances (PFAS) and human health: A review of the literature
Science of the Total Environment · 2020
The study summarizes evidence that PFAS exposure is associated with adverse health effects including immunotoxicity, endocrine disruption, and increased risk of certain cancers.
Read studyPer- and polyfluoroalkyl substances (PFAS) and their associations with obesity, cardiovascular disease, and hypertension in the US population
Environmental Research · 2020
This study identified significant positive associations between serum PFAS concentrations and markers of cardiovascular disease, hypertension, and obesity in the US adult population.
Read studyPer- and polyfluoroalkyl substances (PFAS) and their association with metabolic health: A systematic review and meta-analysis
Environmental Research · 2021
Evidence suggests a positive association between exposure to specific PFAS compounds and increased serum cholesterol and insulin resistance in human populations.
Read studyPFAS exposure and thyroid disease: A systematic review and meta-analysis
Environmental Research · 2021
Meta-analysis indicates that elevated serum PFAS levels are significantly associated with thyroid hormone dysregulation and increased prevalence of thyroid disease in humans.
Read studyPFAS exposure and immune response to vaccines: A systematic review and meta-analysis
Environmental Research · 2021
The analysis demonstrates a significant inverse relationship between PFAS exposure levels and antibody response to various vaccines, indicating potential immunotoxicity.
Read studyImmunotoxicity of per- and polyfluoroalkyl substances (PFAS) in humans: A systematic review
Environmental Health Perspectives · 2021
Analysis indicates that PFAS exposure is significantly associated with suppressed vaccine response and increased risk of infectious diseases in both children and adults.
Read studyExposure to perfluoroalkyl substances and cancer risk in a population-based cohort
International Journal of Cancer · 2022
The study suggests positive associations between specific PFAS exposures and the incidence of certain hormone-related cancers, supporting potential carcinogenic pathways.
Read studyEndocrine-disrupting effects of per- and polyfluoroalkyl substances: A systematic review and meta-analysis
Reviews on Environmental Health · 2020
The review highlights consistent evidence of thyroid hormone disruption and adverse reproductive health effects resulting from PFAS exposure.
Read studyPer- and polyfluoroalkyl substances (PFAS) in blood and the risk of thyroid cancer
Environmental Research · 2021
Epidemiological findings suggest a positive association between serum concentrations of long-chain PFAS and the incidence of thyroid cancer.
Read study| California Prop 65 | not listed | — | — | View |
